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What is Biologics and what are its most dominant types?

Published Date : 2017-08-02

Biologics also referred to as biopharmaceutical is any type of pharmaceutical drug product which is extracted from, manufactured in or semi-synthesized by biological means. Biopharmaceutical differs from completely synthesized pharmaceuticals and include living cells that are used in cell therapy, gene therapies, allergenic, vaccines, blood components, recombinant therapeutic protein, blood, tissues and somatic cells. Biologics can be collected of nuclei acids, proteins, sugars or living tissues and cells or an intricate combination of all these elements. They are secluded form living sources like plants, animals, humans, microbial or fungal.

Terminology that surrounds biologics may vary between groups, with different subdivisions of therapeutics having different terms inside the general biologics category. A recent category of pharmaceuticals know and specialty drugs are drugs that are high in cost and are biologics. The European medicines Agency refers to medicines for humans that are based on tissue engineering, cells or genes as advanced therapy medicinal products, involving somatic-cell therapy medicines, gene therapy medicines, tissue-engineered medicines and various combinations. Cellular biologics and biologics based on genes are often at the cutting edge of biomedical research and can be used for treating diseases that have no other treatment.Biopharmacology is the term that is used sometimes to address the branch of pharmacology that studies biologics.

The earliest forms of biologics are taken from the bodies of animals and other humans. Some of the main biologics consists of:

  • Human reproductive cells
  • Organs and tissue transplants
  • Human breast milk
  • Fecal microbiota
  • Stem cell therapy
  • Antibodies for passive immunization
  • Whole blood and other components of blood

Biologics as category of medicines has had a deep impact on numerous medical fields like gastroenterology, oncology, dermatology, neurology, rheumatology and cardiology. Biologics have added a wide range of therapeutic options for most of these methods in order to treat numerous diseases. However, the introduction of biologic therapeutics complicated issues. Older patients who took biologic therapy for diseases like psoriatic arthritis, ankylosing spondylitis or rheumatoid arthritis are said to be at risk infections that can be life-threatening, inimical cardiovascular diseases and virulence.

Dominant types of biologics include:

  • Hormones such as growth hormone, gonadotrophins, insulin, and glucagon
  • Vaccines such as Hepatitis B surface antigen
  • Interferons such as Interferons-α, -β, -γ
  • Blood factors such as Factor IX and Factor  VIII
  • Products that are Interleukin-based
  • Monoclonal antibodies
  • Additional products like therapeutic enzymes and tumor necrosis factor
  • Thrombolytic agents like tissue plasminogen activator
  • Hematopoietic growth factors such as colony stimulating factors and Erythropoietin

When a new biologics is being introduced, a patent will be applied by the company which is an allowance for the manufacturing rights. This is the major source of recovering the investment made for the development of the biologics.

Crystal Market Research published a report on “Biologics Market by Product, Application and Source Material - Global Industry Analysis and Forecast to 2025” released and accessible at

https://www.crystalmarketresearch.com/report/biologics-market

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