A latest study published in November in the Journal published by Steven Yukl from the San Francisco Veterans Affairs Medical Center with the collaboration with the University of California and the University of San Francisco known as PLOS Pathogens stated that the human mechanism that manages the HIV transcription as well as the latency are different throughout the blood and gut. The research was held in order discover new therapies or treatment for treating HIV. The drug antiretroviral available in the market has proved to increase the life expectancy of people suffering from HIV but the virus can however escape the defense system established by the drug and may cause an infection in some other part of the immune system and cells which leads in formation of a protein called CD4 that causes a major barrier for the treatment. On the other hand CD4 cells are very important to be present in the human blood and gut plays a major role to store these cells. The doctors came across the mechanism responsible for blocking and managing HIV transcription and manage the HIV latency in CD4+T cells present in the gut and the blood. The researchers discovered that these mechanisms have a major role and significance when establishing any new therapies or treatment options in order to cure HIV patient.